Author

Guanqiao Zhang

Zhejiang UniversityORCID 0000-0001-9274-9358Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:deep learning· 2 Organism:human· 2 Assay:proteomics· 2 Assay:protein sequence· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Ruhong ZhouiD· 3 shared Chun ChaniD· 2 shared Ruofan JiniD· 2 shared Yaqi Fu· 2 shared Damiano BurattoiD· 1 shared Hanyao Wang· 1 shared Jingxuan GeiD· 1 shared Kim Hsieh· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersBioinformatics

Ruhong ZhouORCID

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3 papers

Recent·Most cited

Multi-strategies embedded framework for neoantigen vaccine maturation

Guanqiao Zhang, Yaqi Fu, Chun Chan, Ruofan Jin, Yuxuan Yang, Lei Fu, Ruhong Zhou

NEOM improves neoantigen selection by integrating multiple strategies to enhance peptide binding affinity and immunogenic potential.

Scientific Reports · Jan 19, 2026Peer-reviewedBioinformatics

Reengineering the antigen optimization process for superior neoantigen vaccine design

Guanqiao Zhang, Yaqi Fu, Damiano Buratto, Chun Chan, Hanyao Wang, Yuanling Huang, Liquan Huang, Ruhong Zhou

AlphaVacc optimizes neoantigen peptides using deep reinforcement learning, improving binding affinity and T cell response in experimental validation.

bioRxiv · Aug 3, 2025 · PreprintBioinformatics

A Multi-Modal Deep Learning Framework with Both Sequence and Structure for Tumor Antigens Prediction

Ruofan Jin, Jingxuan Ge, Guanqiao Zhang, Ziyan Deng, Kim Hsieh, Tingjun Hou, Ruhong Zhou

MultiTAP improves tumor antigen immunogenicity prediction by integrating sequence and structure features with an attention mechanism, outperforming existing models across diverse HLA phenotypes.

bioRxiv · Nov 6, 2024 · PreprintBiophysics