LetA defines a structurally distinct transporter family involved in lipid trafficking
Cristina Santarossa, Yupeng Li, Sara Yousef, Hale S. Hasdemir, Carlos C. Rodriguez, Max B. Haase, Minkyung Baek, Nicolas Coudray, John G. Pavek, Kimber N. Focke, Annika L. Silverberg, Carmelita Bautista, Johannes T.‐H. Yeh, Michael Thomas Marty, David A. Baker, , Gira Bhabha
The paper determines the structure of E. coli LetAB, identifies LetA as a novel transporter family, and proposes a mechanism for lipid transport using proton-motive force.
bioRxiv · Mar 21, 2025 · PreprintBiophysics