Genetic loss of norepinephrine does not alter adult hippocampal neurogenesis in dopamine β-hydroxylase deficient mice
Darshana Kapri, Krishna C. Vadodaria, Karen S. Rommelfanger, Yvonne E. Ogbonmwan, Larry Cameron Liles, Kimberly A. Fernandes-Thomas, Sonali S. Salvi, Basma Fatima Anwar Husain, David Weinshenker, Vidita A. Vaidya
The paper investigates the effect of genetic NE loss on adult hippocampal neurogenesis and finds no difference in progenitor proliferation or survival in Dbh-/- mice, contrasting with pharmacological NE depletion.
bioRxiv · Sep 14, 2022 · PreprintNeuroscience