Distinct roles of BRCA2 in replication fork protection in response to hydroxyurea and DNA interstrand crosslinks
Kimberly A. Rickman, Raymond J. Noonan, Francis P. Lach, Sunandini Sridhar, Anderson T. Wang, Avinash Abhyankar, Athena L. Huang, Michael C. Kelly, Arleen D. Auerbach, Agata Smogorzewska
This study investigates BRCA2's role in protecting DNA at interstrand crosslinks and shows its distinct function compared to its role in hydroxyurea-induced fork protection.
bioRxiv · Oct 28, 2019Molecular Biology