Developmental BiologyJournal of the American Society of NephrologyPeer-reviewed
DNMT1 in Six2 progenitor cells is essential for transposable element silencing and kidney development
Szu‐Yuan Li, Jihwan Park, Yuting Guan…·Katalin Suszták
This study shows that Dnmt1 is critical for kidney development by maintaining methylation of transposable elements in Six2 progenitor cells, preventing their regression and ERV activation.
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