Somatic aberrations of BRCA1 gene are associated with progressive and stem cell-like phenotype of prostate cancer
Aleksandra Omari, Paulina Nastały, Aneta Bałabas, Michalina Dąbrowska, Beata Bielińska, Sebastian Huss, Klaus Pantel, Axel Semjonow, Elke Eltze, Burkhard Brandt, Natalia Bednarz-Knoll
The paper investigates BRCA1 gene aberrations in prostate cancer, finding that losses correlate with aggressive features and stem cell-like properties, while gains are linked to invasiveness.
bioRxiv · Feb 26, 2018 · PreprintCancer Biology