Allosteric inhibition of CXCR1 and CXCR2 abrogates Th2/Th17-associated Allergic Lung Inflammation in Mice
Koa Hosoki, Annamalai Govindhan, John M Knight, Sanjiv Sur
This study shows that inhibiting CXCR1 and CXCR2 reduces Th2/Th17-driven allergic lung inflammation in mice by blocking cell recruitment and cytokine expression.
bioRxiv · May 13, 2024 · PreprintImmunology