The Role of Conformational Changes in TcmN Aromatase/Cyclase in Polyketide Biosynthesis
Verônica Silva Valadares, Ana Clara S Granja, Luan Carvalho Martins, Krishna Padmanabha Das, Elio A. Cino, Mariana T. Q. Magalhaes, Ana Paula Valente, Haribabu Arthanari, Adolfo Henrique Moraes
This study investigates how conformational changes in TcmN aromatase/cyclase regulate substrate binding and product release during polyketide biosynthesis.
bioRxiv · Mar 1, 2026 · PreprintBiophysics