Removal of developmentally regulated microexons has a minimal impact on larval zebrafish brain morphology and function
Caleb CS Calhoun, Mary ES Capps, Kristie Muya, William C Gannaway, Verdion Martina, Claire L Conklin, Morgan C Klein, Jhodi M Webster, Emma G Torija-Olson, Summer B. Thyme
This study removes 45 microexons in zebrafish using CRISPR/Cas9 and finds minimal developmental impact on brain morphology and function, with some exceptions in specific microexons.
eLife · Nov 18, 2025Peer-reviewedNeuroscience