ZEB2 signaling is essential for ureteral smooth muscle cell differentiation and maintenance
Sudhir Kumar, Xueping Fan, Harshita Pattam, Kun Yan, Easton J. Liaw, Jiayi Ji, Emily Zaltz, Paul Song, Yuqiao Jiang, Yuriko Nishizaki, Yujiro Higashi, Chen‐Leng Cai, Weining Lu
This study shows that ZEB2 is essential for ureteral smooth muscle cell differentiation and maintenance, as its deletion in mice causes hydroureter and hydronephrosis.
bioRxiv · Feb 23, 2025 · PreprintDevelopmental Biology