In Vitro Efficacy of Next Generation Dihydrotriazines and Biguanides Against Babesiosis and Malaria Parasites
Pratap Vydyam, Meenal Chand, Shalev Gihaz, Isaline Renard, Gavin D. Heffernan, Laura R. Jacobus, David P. Jacobus, Kurt W. Saionz, Raju Shah, Hong‐Ming Shieh, Jacek Terpiński, Wenyi Zhao, Emmanuel Cornillot, Choukri Ben Mamoun
This study screens dihydrotriazines and biguanides against Babesia and Plasmodium parasites to identify effective antifolates with broad-spectrum activity and high therapeutic indices.
Antimicrobial Agents and Chemotherapy · Aug 13, 2024Peer-reviewedMicrobiology