Harnessing the regenerative potential of interleukin11 to enhance heart repair
Kwangdeok Shin, Anjelica Rodriguez, Chanul Kim, Isabella M. Silaban, Yu Xia, Jisheng Sun, Chenyang Dong, Sündüz Keleş, Jinhu Wang, Jingli Cao, Junsu Kang
This study identifies IL11's dual role in heart regeneration and fibrosis, showing that combining IL11a induction with ERK inhibition can enhance regeneration while reducing fibrosis.
Nature Communications · Nov 8, 2024Peer-reviewedDevelopmental Biology