Anjelica Rodriguez

The paper identifies a novel epithelial cell type in zebrafish fins, spike cells, and shows their role in maintaining immune cell niche homeostasis through interactions with mpeg1+ immune cells.

The paper introduces a toolkit for precise genome editing in zebrafish, including a subcloning platform and synthetic exon strategy, enabling efficient knock-in of specific genes.

This study identifies IL11's dual role in heart regeneration and fibrosis, showing that combining IL11a induction with ERK inhibition can enhance regeneration while reducing fibrosis.

The paper develops a robust strategy for generating knock-in reporter animals using minicircle technology and an ectopic promoter, improving efficiency and reducing unintended genomic effects.

This study shows that sarcoplasmic calcium dysregulation occurs before structural muscle damage in C. elegans modeling Duchenne muscular dystrophy and that increased activity can improve some muscular parameters but not longevity.