GM-CSF negatively regulates early IL-10 mediated responses
R. H. P. Wilbers, L. B. Westerhof, D. R. van Raaij, G. Smant, J. Bakker, A. Schots
This study shows GM-CSF inhibits IL-10 responses in dendritic cells and macrophages by impairing SOCS3 expression and early TNF suppression, without affecting STAT3 activation.
bioRxiv · Oct 13, 2017Immunology