Structural and biophysical characterization of HNF-1A as a tool to study MODY3 diabetes variants
L. Kind, A. Raasakka, J. Molnes, I. Aukrust, L. Bjorkhaug, P. R. Njolstad, P. Kursula, T. Arnesen
This study structurally and biophysically characterizes HNF-1A variants associated with MODY3 diabetes, showing reduced functionality in three variants compared to wild-type.
bioRxiv · Dec 20, 2021 · PreprintBiochemistry