Defining the Cell Surface Cysteinome using Two-step Enrichment Proteomics
T. Yan, L. Boatner, L. Cui, P. Tontonoz, K. Backus
The paper introduces a two-stage enrichment method called Cys-Surf to profile the cell surface cysteinome, identifying 821 ligandable cysteines and redox-sensitive residues with functional implications.
bioRxiv · Oct 17, 2023Biochemistry