HP1-driven phase separation recapitulates the thermodynamics and kinetics of heterochromatin condensate formation
M. M. Tortora, L. Brennan, G. Karpen, D. Jost
This paper investigates how HP1-driven phase separation forms PCH condensates in vivo, showing that HP1-chromatin interactions and genomic H3K9me2/3 distribution govern their thermodynamics and kinetics.
bioRxiv · Jul 11, 2022 · PreprintBiophysics