Author

L. Bryner

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1

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C. Paulino· 1 shared G. T. Oostergetel· 1 shared R. Dutzler· 1 shared V. Clerico Mosina· 1 shared V. Kalienkova· 1 shared

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2019-2019 · peak 1/yr

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1 shared paperBiochemistry

C. Paulino

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1 paper

Recent·Most cited

Stepwise activation mechanism of the scramblase nhTMEM16 revealed by cryo-EM

V. Kalienkova, V. Clerico Mosina, L. Bryner, G. T. Oostergetel, R. Dutzler, C. Paulino

This study uses cryo-EM to reveal the stepwise activation mechanism of nhTMEM16, showing how Ca2+-binding induces conformational changes that facilitate lipid scrambling.

bioRxiv · Feb 5, 2019Biochemistry