Author

L. C. Ciacchi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Organism:rat· 1

Frequent Co-Authors

A. J. Mathew· 1 shared A. Peter· 1 shared F. Hater· 1 shared H. Callenius· 1 shared H. Ellinghaus· 1 shared I. Finkemeier· 1 shared I. L. Grothaus· 1 shared J. Eirich· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperPlant Biology

A. J. Mathew

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2 papers

Recent·Most cited

N-glycosylation modulates enzymatic activity of Trypanosoma congolense trans-sialidase

J. Rosenau, I. L. Grothaus, Y. Yang, N. Dinesh Kumar, L. C. Ciacchi, S. Kelm, M. Waespy

This study shows that N-glycans on Trypanosoma congolense trans-sialidase affect substrate affinity but not conversion rate, with molecular dynamics revealing structural interactions that enhance enzyme function.

bioRxiv · Dec 13, 2021Biochemistry

A versatile mitochondria isolation- and analysis-pipeline generates 3D nano-topographies and mechano-physical surface maps of single organelles

S. Joshi, F. Hater, J. Eirich, J. Palovaara, H. Ellinghaus, P. Heinkow, H. Callenius, A. Peter, O. Schweser, M. Kubitschke, M. K. Madduri, A. J. Mathew, L. C. Ciacchi, J. Kirstein, K. Maedler, , R. Gross-Hardt

This paper introduces a pipeline for isolating and analyzing single mitochondria to generate 3D nano-topographies and mechano-physical surface maps, revealing diversity in mitochondrial properties.

bioRxiv · Oct 31, 2021 · PreprintPlant Biology