Author

L. C. Franssen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

M. A. Chaplain· 2 shared A. F. Burgess· 1 shared M. A. J. Chaplain· 1 shared N. Sfakianakis· 1 shared T. Lorenzi· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 4 mutual co-author links

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2 shared papersCancer Biology

M. A. Chaplain

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3 papers

Recent·Most cited

A novel 3D atomistic-continuum cancer invasion model: In silico simulations of an in vitro organotypic invasion assay

N. Sfakianakis, L. C. Franssen, M. A. J. Chaplain

The paper develops a 3D hybrid model to simulate cancer cell invasion in an in vitro assay, incorporating phenotypic variation and EMT/MET transitions.

bioRxiv · Aug 22, 2020Cancer Biology

A mathematical multi-organ model for bidirectional epithelial-mesenchymal transitions in the metastatic spread of cancer

L. C. Franssen, M. A. Chaplain

The paper develops a mathematical model of cancer metastasis that incorporates epithelial-mesenchymal transitions and their impact on tumor spread across multiple organs.

bioRxiv · Aug 28, 2019Cancer Biology

A mathematical framework for modelling the metastatic spread of cancer

L. C. Franssen, T. Lorenzi, A. F. Burgess, M. A. Chaplain

This paper develops a mathematical framework to model metastatic spread of cancer, showing that MT1-MMP drives invasion rather than MMP-2.

bioRxiv · Nov 14, 2018Cancer Biology