Author

L. C. Watkins

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Research Focus:protein folding & dynamics· 2 Organism:virus· 2 Approach:biophysical modeling· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

G. A. Voth· 3 shared W. F. DeGrado· 2 shared H. T. Kratochvil· 1 shared J. L. Thomaston· 1 shared J. M. Nicoludis· 1 shared L. Liu· 1 shared M. Hong· 1 shared M. Mravic· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersBiophysics

G. A. Voth

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Transient Water Wires Mediate Selective Proton Conduction in Designed Channel Proteins

H. T. Kratochvil, L. C. Watkins, M. Mravic, N. H. Somberg, J. L. Thomaston, J. M. Nicoludis, L. Liu, M. Hong, G. A. Voth, W. DeGrado

The paper designs proton-conducting channels that use transient water wires to achieve high selectivity for protons over sodium ions.

bioRxiv · Mar 28, 2022Biophysics

Multiscale Simulation of an Influenza A M2 Channel Mutant Reveals Key Features of Its Markedly Different Proton Transport Behavior

L. C. Watkins, W. F. DeGrado, G. A. Voth

This study uses multiscale simulations to analyze how the D44N mutation in the influenza A M2 channel alters proton transport behavior compared to the wild-type.

bioRxiv · Sep 7, 2021Biophysics

Influenza A M2 Inhibitor Binding Understood through Mechanisms of Excess Proton Stabilization and Channel Dynamics

L. C. Watkins, W. F. DeGrado, G. A. Voth

This paper investigates how influenza A M2 inhibitors bind by analyzing proton stabilization and channel dynamics using MS-RMD simulations.

bioRxiv · Jun 19, 2020Biophysics