Co-translational protein targeting facilitates centrosomal recruitment of PCNT during centrosome maturation
G. Sepulveda, M. Antkowiak, I. Brust-Mascher, K. Mahe, T. Ou, N. Castro, L. N. Christensen, L. Cheung, D. Yoon, B. Huang, L.-E. Jao
The paper shows PCNT is co-translationally targeted to centrosomes during mitosis by cytoplasmic dynein, with ASPM also showing similar targeting to spindle poles.
bioRxiv · Dec 30, 2017Cell Biology