Progressive impairments in executive function in the APP/PS1 model of Alzheimer’s disease as measured by translatable touchscreen testing
A. Shepherd, J. K. H. Lim, V. H. Y. Wong, A. M. Zeleznikow-Johnston, L. Churilov, C. T. O. Nguyen, B. V. Bui, A. J. Hannan, E. L. Burrows
The paper assesses executive function in APP/PS1 mice using touchscreen tasks and finds age-related deficits in extinction and reversal, independent of visual impairments.
bioRxiv · Aug 21, 2019Animal Behavior & Cognition