Ormdl3 regulation of specific ceramides is dispensable for β-cell function and glucose homeostasis under obesogenic conditions
L. D. Hurley, H. Lee, G. Wade, J. Simcox, F. Engin
This study shows that loss of Ormdl3 in β-cells does not affect glucose homeostasis on standard diet but increases specific ceramide levels under high fat diet.
bioRxiv · Feb 11, 2023 · PreprintCell Biology