DNA Double-Strand Break Movement in Heterochromatin Depends on the Histone Acetyltransferase dGcn5.
A. Kendek, A. Sandron, J.-P. Lambooij, S. U. Colmenares, S. M. Pociunaite, I. Gooijers, L. de Groot, G. Karpen, A. Janssen
This study shows that dGcn5-mediated H3K9ac enrichment at heterochromatic DSBs is essential for their movement to the periphery and proper repair.
bioRxiv · Nov 30, 2023Cell Biology