Author

L. E. Cowen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Assay:cryo-EM· 1 Organism:fungi (other)· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Urisman· 1 shared E. V. Dang· 1 shared H. D. Madhani· 1 shared J. W. Lou· 1 shared K. R. Iyer· 1 shared M. T. Mazhab-Jafari· 1 shared P. Basso· 1 shared S. M. N. Hasan· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperMicrobiology

A. Urisman

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Deep tissue infection by an invasive human fungal pathogen requires novel lipid-based suppression of the IL-17 response

P. Basso, E. V. Dang, A. Urisman, H. D. Madhani, L. E. Cowen, S. M. Noble

This study identifies a mechanism by which Candida albicans suppresses the host IL-17 response through lipid-mediated immunosuppression, leading to invasive disease.

bioRxiv · Feb 7, 2022Microbiology

Electron cryomicroscopy observation of acyl carrier protein translocation in type I fungal fatty acid synthase

J. W. Lou, K. R. Iyer, S. M. N. Hasan, L. E. Cowen, M. T. Mazhab-Jafari

The paper uses electron cryomicroscopy to observe ACP translocation in fungal FAS, showing substrate-dependent conformational changes in the ER site.

bioRxiv · May 14, 2019Biophysics