ImmunologybioRxivPreprint
Lung tumor-infiltrating Treg have divergent transcriptional profiles and function linked to checkpoint blockade response
A. G. Dykema, J. Zhang, B. Zhang…·K. N. Smith
The paper identifies 10 subsets of lung cancer-infiltrating Tregs, showing one subset is suppressive and linked to anti-PD-1 resistance while another is Th1-like and associated with PD-1 response.