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Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
9 papers
Recent·Most cited
H. Yu, H. Nishio, J. Barbi, M. Mitchell-Flack, P. D. A. Vignali, Y. Zheng, A. Lebid, K.-Y. Chang, J. Fu, M. Higgins, C.-T. Huang, X. Zhang, Z. Li, L. Blosser, A. Tam, , D. M. Pardoll
This study shows that neuritin modulates T cell electrical and metabolic states, influencing immune tolerance and immunity.
bioRxiv · Jan 31, 2024Immunology
P. K. Um, M. Praharaj, K. A. Lombardo, T. Yoshida, A. Matoso, A. S. Baras, L. Zhao, G. Srikrishna, J. Huang, P. Prasad, M. Kates, D. McConkey, D. M. Pardoll, W. R. Bishai, T. J. Bivalacqua
This study evaluates a recombinant BCG strain that releases a STING agonist, showing improved antitumor efficacy in bladder cancer models compared to wild-type BCG.
bioRxiv · Dec 15, 2023 · PreprintCancer Biology
A. G. Dykema, J. Zhang, B. Zhang, L. S. Cheung, Z. Zeng, C. M. Cherry, T. Li, J. X. Caushi, M. Nishimoto, S. Connor, Z. Ji, A. J. Munoz, W. Hou, W. Zhan, D. Singh, , K. N. Smith
The paper identifies 10 subsets of lung cancer-infiltrating Tregs, showing one subset is suppressive and linked to anti-PD-1 resistance while another is Th1-like and associated with PD-1 response.
bioRxiv · Dec 13, 2022 · PreprintImmunology
D. VanDyke, M. Iglesias, J. Tomala, A. Young, J. Smith, J. A. Perry, E. Gebara, A. R. Cross, L. S. Cheung, A. G. Dykema, B. T. Orcutt-Jahns, T. Henclova, J. Golias, J. Balolong, L. M. Tomasovic, , J. B. Spangler
The paper engineers a cytokine/antibody fusion protein that selectively expands regulatory T cells and protects against autoimmune diseases in mouse models.
bioRxiv · May 29, 2022Bioengineering
D. R. Maestas, L. Chung, J. Han, X. Wang, S. D. Sommerfeld, E. Moore, H. Hieu Nguyen, J. C. Mejias, A. N. Pena, H. Zhang, J. S. T. Hooks, A. F. Chin, J. I. Andorko, C. Berlicke, K. Krishnan, , J. H. Elisseeff
This study develops a regenerative immunotherapy using helminth-derived soluble egg antigen to promote tissue repair in multiple injury models.
bioRxiv · May 2, 2022 · PreprintBioengineering
C. Cherry, J. I. Andorko, K. Krishnan, J. C. Mejias, H. H. Nguyen, K. B. Stivers, E. F. Gray-Gaillard, A. Ruta, N. Hamada, M. Hamada, I. Sturmlechner, S. Trewartha, J. H. Michel, L. D. Huyer, M. T. Wolf, , J. H. Elisseeff
The paper develops a transfer learning approach to identify senescent cells across species and tissues using an in vivo-derived gene expression signature, revealing conserved and tissue-specific senescence features.
bioRxiv · Mar 22, 2022 · PreprintBioengineering
J. Han, C. Cherry, J. C. Mejias, A. Ruta, D. R. Maestas, A. Pena, H. H. Nguyen, B. Yang, E. Gray-Gaillard, N. Rutkowski, K. Krishnan, A. J. Tam, E. J. Fertig, F. Housseau, S. Ganguly, , J. H. Elisseeff
This study shows that age-related senescent T cells promote type 3 immunity, which inhibits tissue repair, and that blocking this pathway improves healing in older animals.
bioRxiv · Aug 17, 2021 · PreprintBioengineering
S. D. Sommerfeld, C. Cherry, R. M. Schwab, L. Chung, D. R. Maestas, P. Laffont, J. E. Stein, A. Tam, F. Housseau, J. M. Taube, D. M. Pardoll, P. Cahan, J. H. Elisseeff
The paper uses single-cell RNA sequencing to identify distinct macrophage subsets in regenerative and fibrotic environments, revealing new phenotypes and potential therapeutic targets.
bioRxiv · May 20, 2019Immunology
L. Chung, D. Maestas, A. Lebid, A. Mageau, G. D. Rosson, X. Wu, M. T. Wolf, A. Tam, X. Wang, I. Vanderzee, J. I. Andorko, R. Narain, K. Sadtler, H. Fan, D. Cihakova, , J. Elisseeff
This study identifies IL17 and senescence as regulators of the foreign body response, showing their roles in fibrosis and potential as therapeutic targets.
bioRxiv · Apr 11, 2019Immunology