PathologybioRxivPreprint
Loss-of-function mutation in human Oxidation Resistance gene 1 disrupts the spatial-temporal regulation of histone arginine methylation in early brain development
X. Lin, W. Wang, M. Yang…·M. Bjoras
This study identifies a loss-of-function mutation in OXR1 causing neurodevelopmental disorders and shows its role in regulating histone arginine methylation in brain organoids.
DOI 10.1101/2022.05.24.493324