Author

L. Fesüs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 5

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Assay:bulk RNA-seq· 5 Organism:human· 5 Research Focus:cell signaling & trafficking· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2

Frequent Co-Authors

E. Kristof· 5 shared R. Arianti· 5 shared A. Shaw· 3 shared A. Vamos· 3 shared B. A. Vinnai· 3 shared I. Csomos· 3 shared S. Poliska· 3 shared A. Guba· 2 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersCell Biology

E. Kristof

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5 papers

Recent·Most cited

Extracellular thiamine concentration influences thermogenic competency of differentiating neck area-derived human adipocytes

B. A. Vinnai, R. Arianti, F. Györy, L. Fesüs, E. Kristof

This study shows that extracellular thiamine concentration during adipocyte differentiation affects thermogenic gene expression and mitochondrial function in human neck-derived adipocytes.

bioRxiv · Apr 13, 2023Cell Biology

Human Abdominal Subcutaneous-Derived Active Beige Adipocytes Carrying FTO rs1421085 Obesity-Risk Alleles Exert Lower Thermogenic Capacity

A. Vamos, R. Arianti, B. A. Vinnai, R. Alrifai, A. Shaw, S. Poliska, A. Guba, E. Csosz, I. Csomos, G. Mocsar, C. Lanyi, Z. Balajthy, L. Fesüs, E. Kristof

The paper investigates how FTO rs1421085 obesity-risk alleles affect thermogenic capacity in human beige adipocytes, finding reduced thermogenesis and gene expression in CC carriers.

bioRxiv · Jan 30, 2023Cell Biology

Availability of abundant thiamine determines efficiency of thermogenic activation in human neck area derived adipocytes

R. Arianti, B. A. Vinnai, F. Gyory, A. Guba, E. Csosz, E. Kristof, L. Fesüs

This study shows that thiamine availability is critical for efficient thermogenic activation in human deep neck adipocytes, as it supports UCP1 function and thermogenic gene induction.

bioRxiv · May 5, 2022Cell Biology

BMP7 increases UCP1-dependent and independent thermogenesis with a unique gene expression program in human neck area derived adipocytes

A. Shaw, B. Toth B, R. Arianti, I. Csomos, S. Poliska, A. Vamos, Z. Bacso, F. Gyory, L. Fesüs, E. Kristof

This study shows BMP7 enhances thermogenesis in human neck adipocytes through both UCP1-dependent and independent mechanisms, upregulating genes like ACAN, CRYAB, and ID1.

bioRxiv · Sep 27, 2021Cell Biology

Irisin stimulates the release of CXCL1 from differentiating human subcutaneous and deep-neck derived adipocytes via upregulation of NFκB pathway

A. Shaw, B. B. Toth, R. Kiraly, R. Arianti, I. Csomos, S. Poliska, A. Vamos, I. R. Korponay-Szabo, Z. Bacso, F. Györy, L. Fesüs, E. Kristof

This study shows irisin increases CXCL1 release from human adipocytes via NFκB pathway activation, enhancing endothelial cell adhesion and potentially improving vascularization.

bioRxiv · Jul 6, 2021Cell Biology