Directing multicellular organization by varying the aspect ratio of soft hydrogel microwells
G. J. Pahapale, J. Tao, M. Nikolic, S. Gao, G. Scarcelli, S. Sun, L. H. Romer, D. H. Gracias
This study shows that endothelial cells self-organize into ring-like patterns on hydrogel microwells based on geometry and substrate stiffness, independent of chemical cues.
bioRxiv · Sep 17, 2021Bioengineering