A role for phagocytosis in inducing cell death during thymocyte negative selection
N. S. Kurd, L. K. Lutes, J. Yoon, I. L. Dzhagalov, A. Hoover, E. A. Robey
This study shows that phagocytosis enhances negative selection of autoreactive thymocytes by promoting their death, with more efficient elimination when phagocytes also present the negative selecting peptide.
bioRxiv · Apr 30, 2019Immunology