Author

L. Lorusso

Health Canada

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Andrea Rowan‐CarrolliD· 2 shared Antony John WilliamsiD· 2 shared Byron Yu-Lin Kuo· 2 shared Carole Lyn YaukiD· 2 shared Ella AtlasiD· 2 shared Ivy D. Moffat· 2 shared Julie Bourdon-Lacombe· 2 shared Karen LeingartneriD· 2 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Andrea Rowan‐CarrollORCID

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2 papers

Recent·Most cited

High-throughput transcriptomics and benchmark concentration modeling for potency ranking of per- and polyfluoroalkyl substances (PFAS) in exposed human liver cell spheroids

A.J.F. Reardon, Andrea Rowan‐Carroll, Stephen Ferguson, Karen Leingartner, Rémi Gagné, Byron Yu-Lin Kuo, Antony John Williams, L. Lorusso, Julie Bourdon-Lacombe, Richard Carrier, Ivy D. Moffat, Carole Lyn Yauk, Ella Atlas

The paper uses high-throughput transcriptomics and benchmark concentration modeling to rank PFAS potency in human liver spheroids based on gene expression changes.

bioRxiv · Oct 20, 2020 · PreprintGenomics

High-throughput transcriptomic evaluation of per- and polyfluoroalkyl substances (PFAS) in primary human liver spheroids to inform read-across

Andrea Rowan‐Carroll, A. Reardon, Karen Leingartner, Rémi Gagné, Antony John Williams, M.J. Meier, Byron Yu-Lin Kuo, Julie Bourdon-Lacombe, Ivy D. Moffat, Richard Carrier, Andy Nong, L. Lorusso, Stephen Ferguson, Ella Atlas, Carole Lyn Yauk

This study evaluates the transcriptomic effects of four PFAS in human liver spheroids to compare their toxicity and inform risk assessment.

bioRxiv · Oct 15, 2020 · PreprintGenomics