Cortical bone gain following loading is site-specifically enhanced by prior and concurrent disuse in aged male mice
G. Galea, P. J. Delisser, L. Meakin, L. Lanyon, J. S. Price, S. H. Windahl
This study shows that disuse enhances cortical bone gain from loading in aged male mice, but not trabecular bone gain in old females, revealing sex-specific effects of disuse on bone anabolic responses.
bioRxiv · Jul 17, 2019Physiology