A Novel Xenonucleic Acid Mediated Molecular Clamping Technology for Early Colorectal Cancer Screening
Q. Sun, L. Pastor, J. Du, M. Powell, A. Zhang, W. Bodmer, J. Wu, S. Zheng, M. Y. Sha
This paper develops a molecular clamping assay called ColoScape for early colorectal cancer detection using XNA-mediated qPCR, showing high sensitivity and specificity in clinical samples.
bioRxiv · May 15, 2020Cancer Biology