ImmunologybioRxiv
Transcriptome profiling reveals CD73 and age-driven changes in neutrophil responses against Streptococcus pneumoniae
M. Bhalla, L. R. Heinzinger, O. B. Morenikeji…·E. N. Bou Ghanem
This study identifies CD73 and age-related transcriptional changes in neutrophils during Streptococcus pneumoniae infection, showing reduced immune responses and impaired bacterial killing in aged and CD73-deficient mice.
DOI 10.1128/iai.00258-21