SREBP1 activation contributes to fatty acid accumulations in necroptosis
D. Lu, L. R. Parisi, O. Gokcumen, G. E. Atilla-Gokcumen
This study shows SREBP1 activation leads to VLCFA accumulation, which worsens necroptosis by increasing membrane permeabilization.
bioRxiv · Aug 22, 2022 · PreprintCell Biology