IER5, a DNA-damage response gene, is required for Notch-mediated induction of squamous cell differentiation
L. Pan, M. E. Lemieux, T. Thomas, J. M. Rogers, W. Lee, C. Johnson, L. Sholl, A. P. South, J. A. Marto, G. O. Adelmant, S. C. Blacklow, J. C. Aster
The paper identifies IER5 as a Notch-induced DNA-damage response gene required for squamous cell differentiation and shows its interaction with PP2A subunit PPP2R2A.
bioRxiv · Apr 21, 2020Cancer Biology