TET2 binding to enhancers facilitates transcription factor recruitment in hematopoietic cells
K. Rasmussen, I. Berest, S. Kessler, K. Nishimura, L. Simon-Carrasco, G. S. Vassilou, M. T. Pedersen, J. Christensen, J. Zaugg, K. Helin
This study shows TET2 binding to enhancers in hematopoietic cells supports transcription factor recruitment, and its loss disrupts chromatin binding of CDX4, linking epigenetic regulation to disease.
bioRxiv · May 31, 2018Cancer Biology