Author

J. Christensen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

A. Athanas· 1 shared A. D. Hargreaves· 1 shared A. Khodadadi-Jamayran· 1 shared A. Payne· 1 shared B. A. Fox· 1 shared B. G. Neel· 1 shared C. Cornelssen· 1 shared C. Fedele· 1 shared

Activity by Year

2016-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCancer Biology

A. Athanas

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Development of an MR-guided focused ultrasound (MRgFUS) lesioning approach for small and deep structures in the rat brain

C. Cornelssen, A. Payne, D. Parker, M. Alexander, R. Merrill, S. Senthilkumar, J. Christensen, K. S. Wilcox, H. Odeen, J. D. Rolston

This paper develops an MR-guided focused ultrasound lesioning method for small and deep brain structures in rats, achieving improved targeting accuracy.

bioRxiv · Oct 11, 2023 · PreprintBioengineering

Combined Inhibition of SHP2 and CXCR1/2 Promotes Anti-Tumor T Cell Response in NSCLC

K. H. Tang, S. Li, A. Khodadadi-Jamayran, J. Jen, H. Han, K. Guidry, T. Chen, Y. Hao, C. Fedele, J. Zebala, D. Maeda, J. Christensen, P. Olson, A. Athanas, K.-K. Wong, B. G. Neel

This study shows that combining SHP2 and CXCR1/2 inhibitors enhances anti-tumor T cell responses in NSCLC by reducing immunosuppressive gMDSCs and promoting effector T cells.

bioRxiv · Mar 21, 2021Cancer Biology

TET2 binding to enhancers facilitates transcription factor recruitment in hematopoietic cells

K. Rasmussen, I. Berest, S. Kessler, K. Nishimura, L. Simon-Carrasco, G. S. Vassilou, M. T. Pedersen, J. Christensen, J. Zaugg, K. Helin

This study shows TET2 binding to enhancers in hematopoietic cells supports transcription factor recruitment, and its loss disrupts chromatin binding of CDX4, linking epigenetic regulation to disease.

bioRxiv · May 31, 2018Cancer Biology

Genome sequence of a diabetes-prone desert rodent reveals a mutation hotspot around the ParaHox gene cluster

A. D. Hargreaves, L. Zhou, J. Christensen, F. Marletaz, S. Liu, F. Li, P. G. Jansen, E. Spiga, M. T. Hansen, S. V. Horn Pedersen, S. Biswas, K. Serikawa, B. A. Fox, W. R. Taylor, J. F. Mulley, , P. W. H. Holland

The paper sequences the genome of a diabetes-prone desert rodent and identifies a mutation hotspot around the ParaHox gene cluster, including the Pdx1 gene, showing extreme divergence due to GC-biased mutation.

bioRxiv · Dec 17, 2016Evolutionary Biology