Aminomethanesulfonic acid illuminates the boundary between full and partial agonists of the pentameric glycine receptor
L. Sivilotti, J. Ivica, H. Zhu, R. Lape, E. Gouaux
This study investigates aminomethanesulfonic acid (AMS) as an agonist of the glycine receptor, showing it acts as a full agonist with high efficacy and provides insights into agonist efficacy mechanisms.
bioRxiv · May 3, 2022Biophysics