Augmenting CAR NK cell Anti-tumor Activity by Synapse Tuning
P. Chockley, J. Ibanez, G. Krenciute, L. Talbot, S. Gottschalk
This study enhances CAR NK cell anti-tumor activity by modifying CAR synapses with a PDZ binding motif to improve synapse formation and tumor killing.
bioRxiv · Oct 26, 2022Immunology