Amino acid usage and tRNA expression underlies proteome adaptation in Plasmodium falciparum
Q. Li, L. Vetter, Y. Veith, E. Christ, A. Vegvari, C. Sahin, U. Ribacke, M. Wahlgren, J. Ankarklev, O. Larsson, S. C. L. Chan
The paper shows that Plasmodium falciparum adjusts its tRNA profile and codon usage to adapt to amino acid availability from hemoglobin digestion, affecting protein synthesis and proliferation.
bioRxiv · Mar 20, 2023Microbiology