Author

C. Sahin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:protein folding & dynamics· 4 Assay:protein structure· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Organism:E. coli· 1

Frequent Co-Authors

M. Landreh· 4 shared D. Lama· 3 shared A. Rising· 2 shared D. P. Lane· 2 shared G. Chen· 2 shared G. V. Gese· 2 shared J. Johansson· 2 shared K. Teilum· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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4 shared papersBiochemistry

M. Landreh

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A suicidal and extensively disordered luciferase with a bright luminescence

F. M. Dijkema, M. I. Escarpizo-Lorenzana, M. K. Nordentoft, H. C. Rabe, C. Sahin, M. Landreh, R. M. Branca, E. S. Sorensen, B. S. Christensen, A. Prestel, K. Teilum, J. R. Winther

This paper investigates the structure and mechanism of Gaussia luciferase, revealing its disordered structure and identifying key residues for light production and inactivation.

Protein Science · Jul 18, 2024Peer-reviewedBiochemistry

Amino acid usage and tRNA expression underlies proteome adaptation in Plasmodium falciparum

Q. Li, L. Vetter, Y. Veith, E. Christ, A. Vegvari, C. Sahin, U. Ribacke, M. Wahlgren, J. Ankarklev, O. Larsson, S. C. L. Chan

The paper shows that Plasmodium falciparum adjusts its tRNA profile and codon usage to adapt to amino acid availability from hemoglobin digestion, affecting protein synthesis and proliferation.

bioRxiv · Mar 20, 2023Microbiology

A grappling hook interaction balances self-assembly and chaperone activity of Nucleophosmin 1

M. Saluri, A. Leppert, G. V. Gese, C. Sahin, D. Lama, M. Kaldmae, G. Chen, A. Elofsson, T. M. Allison, M. Arsenian-Henriksson, D. P. Lane, J. Johansson, B. M. Hallberg, M. Landreh

The paper investigates how NPM1 self-assembly and chaperone activity interact, finding that oligomerization modulates its ability to prevent amyloid formation.

bioRxiv · Sep 29, 2022 · PreprintBiophysics

Mass spectrometry of RNA-binding proteins during liquid-liquid phase separation reveals distinct assembly mechanisms and droplet architectures

C. Sahin, A. Motso, X. Gu, H. Feyrer, D. Lama, T. Arndt, A. Rising, G. V. Gese, B. M. Hällberg, E. G. Marklund, N. P. Schafer, K. Petzold, K. Teilum, P. G. Wolynes, M. Landreh

The paper uses mass spectrometry and simulations to study phase separation of RNA-binding proteins, revealing distinct assembly mechanisms and droplet structures.

bioRxiv · Sep 28, 2022Biophysics

A spindle and thread-mechanism unblocks translation of N-terminally disordered proteins

M. Kaldmae, T. Vosselman, X. Zhong, D. Lama, G. Chen, M. Saluri, N. Kronqvist, J. W. Siau, A. S. Ng, F. J. Ghadessy, P. Sabatier, B. Vojtesek, M. Sarr, C. Sahin, N. Osterlund, , M. Landreh

This study shows that fusing disordered proteins to an engineered spider silk domain improves their translation efficiency and activity in cells.

bioRxiv · Feb 22, 2021 · PreprintBiochemistry