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L. Weidmann

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Evolutionary Biology· 1

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Assay:protein sequence· 1 Approach:statistical model· 1

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A. N. Lupas· 1 shared O. Kohlbacher· 1 shared T. Dijkstra· 1 shared

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1 shared paperEvolutionary Biology

A. N. Lupas

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Minor deviations from randomness have huge repercussions on the functional structuring of sequence space

L. Weidmann, T. Dijkstra, O. Kohlbacher, A. N. Lupas

The paper compares the distribution of natural protein sequences to random models, finding that natural sequences are largely random in global sequence space when accounting for amino acid composition.

bioRxiv · Jun 27, 2021 · PreprintEvolutionary Biology