Single-cell analysis identifies TOP2α as a critical regulator of G2/M entry and differentiation-dependent productive HPV replication
Arushi Vats, Olga Rozhok, Laimonis Laimins
The paper identifies TOP2α as a critical regulator of HPV genome amplification during differentiation by analyzing single-cell RNA-seq data from HPV-infected keratinocytes.
bioRxiv · Sep 24, 2026 · PreprintMicrobiology