Functional and structural characterization of H105Y mutation in MtrR protein of Neisseria gonorrhoeae
Divya Sachdev, Indu Kumari, Madhu Chopra, Laishram R. Singh, Daman Saluja
This study investigates the H105Y mutation in MtrR of Neisseria gonorrhoeae, showing it reduces DNA binding and increases antibiotic resistance by altering protein structure and enhancing antibiotic binding.
bioRxiv · Jul 7, 2020 · PreprintMicrobiology