Vascularized Brain Assembloids with Enhanced Cellular Complexity Provide Insights into The Cellular Deficits of Tauopathy
Simeon Kofman, Xiaohuan Sun, Victor C. Ogbolu, Larisa Ibric, Liang Qiang
This paper introduces vascularized brain assembloids to study tauopathy, showing increased tau pathology and microglia activation in mutant hiPSC-derived models.
bioRxiv · Jun 30, 2023 · PreprintNeuroscience