Liang Qiang

This study uses isogenic hiPSC-derived motor cortical organoids to identify HDAC6 hyperactivation as a key driver of SPG4 pathology and a potential therapeutic target.

This study generates and tests astrocyte progenitor cells from hiPSCs, showing their safe survival and integration in spinal cord transplants without adverse effects.

The paper shows tau and MAP6 have opposing roles in neuronal development by regulating microtubule stability and dynamics in cultured neurons and in vivo.

This study investigates the reprogramming of astrocytes to neurons in spinal cord injury, showing higher in vitro efficiency than in vivo.

This paper introduces vascularized brain assembloids to study tauopathy, showing increased tau pathology and microglia activation in mutant hiPSC-derived models.