Author

Laura Casares Perez

University of Dundee

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Cancer Biology· 1

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Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

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Aileen B. FrostiD· 1 shared Alessio CiulliiD· 1 shared Andrea Stingu· 1 shared Anju Kombara· 1 shared Christiane C. KofinkiD· 1 shared Claire WhitworthiD· 1 shared Emelyne DiersiD· 1 shared Georg Dahmann· 1 shared

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1 shared paperCancer Biology

Aileen B. FrostORCID

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1 paper

Recent·Most cited

Cancer BiologyACS Chemical BiologyPeer-reviewedJul 3, 2024

Confounding factors in targeted degradation of short-lived proteins

Vesna Vetma, Laura Casares Perez, Ján Eliaš…·Manfred Koegl

This study shows that the natural half-life of a target protein significantly affects degradation by degrader agents and highlights confounding factors in screening for protein degraders.

53 citationstop 2%

statistical modeldrug response / drug discovery

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